PDE-5
Inhibitors for Impotence
When it comes to treating impotence problems, there is one family
of medications that has proven to be the most effective method
for dealing with the problem.
This family of drugs is known as PDE-5 inhibitors,
and they work by helping the muscles of the penis and the blood
vessels of the penis to relax, allowing for
an erection to occur with less trouble than normal. Most of
these drugs have shown to be effective in roughly eighty percent
of
all cases of erectile dysfunction, and for that reason, many
men turn to them in order to achieve a cure for their problem
with impotence. In this article, we'll be discussing some of
the more commonly used PDE-5 inhibitors for use in dealing
with a problem with erectile dysfunction. The type of PDE-5
inhibitor that you are probably the most familiar
with is known as Viagra. Made by the Pfizer Corporation, the
drug has been used for years to help men to achieve erections.
It was one of the first PDE-5 inhibitors on the market, and millions
of men have been aided by the pill. It's an oral medication,
and it begins to work within a half hour to an hour after ingestion.
The erections experienced by the pill
can last for up to four hours after the effects begin,
and between sixty and seventy
percent of all men with erectile dysfunction that take Viagra
have been shown to benefit, even those who have had a long-term
history of impotence. Cialis was one of the next PDE-5
inhibitors to make it to the market. It was approved for use by the United
States Food and
Drug Administration late in 2003, and it was developed by a joint
effort between the pharmaceutical company known as Eli Lilly
and the bio-tech firm called ICOS. Similar to Viagra in many
ways, it has a few benefits that put it ahead of Viagra, leading
many to call it a form of 'Super-Viagra".
Where Viagra takes
a half hour to an hour before the effects are achieved, Cialis
begins to work within ten to twenty minutes after ingestion.
Also, the effects of Cialis last longer than Viagra, with erections
attainable for a full thirty six hours after taking the pill.
Food and alcohol consumption don't affect the efficiency of
the pill, and it's beginning to erode Viagra's market share
as the
top erection medication. Last, but not least, in the types of PDE-5
inhibitors available
is a drug known as Levitra. It's a type of inhibitor that has
shown to be of use for those who are unable to take Viagra. One
negative aspect of Levitra is the fact that you need to watch
what you eat before taking the pill. Clinical studies suggest
that the pill is most effective when taken at least three hours
after a meal, as food can interfere with its efficacy. The drug
takes between thirty and sixty minutes to begin working and the
effects can last for up to five hours. New Impotence
Drug Shows Promise
There is a new impotence drug that the FDA is moving
towards approval. The new drug is called Uprima and it
will be used to treat male impotence, otherwise known
as erectile dysfunction. This new drug is manufactured
by TAP Pharmaceuticals. If the FDA confirms the approval
of Uprima, it is expected that this new drug will join
the ranks of Viagra, which is manufactured by Pfizer.
How does Uprima work?
Uprima works
by stimulating parts of the brain that produces the
chemical known as dopamine.
The increased production of dopamine allows the user
to achieve an erection with greater ease. Originally,
Uprima was developed for use to treat Parkinson's
and other motor diseases. Although Uprima shows great promise for treating erectile
dysfunction disorders, it does have some side effect.
There are two primary side effects that have been noted.
These two side effects are nausea and hypertension. The
nausea can range from mild to severe. Studies have shown
that Uprima can also cause extreme drop in blood pressure
that can result in fainting and weakness. These potential
side effects may be greatly exacerbated by alcohol intake.
Currently, the FDA is considering putting a warning label
on Uprima to warn users about the dangers of alcohol
use and taking Uprima.
What are the main differences between using Viagra and
Uprima?
Viagra has proved massively successful,
although it too carries certain side effects and health
risks.
However, Uprima works differently than Viagra. One
of the main differences between these two drugs is
that
Uprima tends to work faster. This is because Uprima
is taken by dissolving under the tongue. This causes
the
effect of the drug to enter the blood stream faster
than taking it in pill form. According to recent studies,
Uprima takes effect in roughly 15 to 20 minutes. Compare
this to Viagra, which can take up to an hour to take
total effect. In order to be prescribed Uprima, a patient must first
be diagnosed with erectile dysfunction. Erectile dysfunction
is must be diagnosed by a physician; usually an urologist
will perform the examination. The initial consultation
will usually consist of a physical examination, and your
physician may choose to order certain lab tests. The
physician will probably take a sexual history. They will
want to know whether you feel pain during an erection,
if the erection is irregular, and whether you ever wake
in the morning with an erection.
These questions are
meant to narrow the possibilities to find the underlying
cause for erectile dysfunction. Erectile dysfunction
can have several causes. The disorder may be physiological
in nature, or it may have its roots in psychological
problems. Whatever the underlying cause, working with
your physician can help identify the problem and open
the doors to successful treatment. With the development of new treatments such as Viagra
and now Oprima, erectile dysfunction patients now have
more safe and effective treatment options than ever before.
Your physician will help you find the right treatment
option for your particular circumstances.
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